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Cell-in-a-Box®技術應用舉例

          學術研究:3D細胞培養、多種細胞共同培養、藥物研發、基於細胞的研究等
          生物科技/醫藥:幹細胞、疫苗、抗體、生物大分子藥物等細胞産品或産物的

                              生産
          醫療保健:癌症、糖尿病、心血管病、退行性疾病、傳染病、遺傳病等的治療


                                                   BIOTECHNOLOGY                                                    3D Cell Culture

                                                   Protection, Compartmertateation,
                    HEALTHCARE                     PreFiltration, Storage

                  Successful clinical trials over 40   -Protection of sensitive cell lines
                  scientific publications         inside bioreactors
                  -Cancer                                                      RESEARCH
                  -Stem cell therapy
                  -Metabolic disease                                          Tools for Scientists
                  -Infection disease                                          -New animal models
                  -Cardiovascular disease                                     -Research kit for
                  -Transplantation                                            encapsulation of cells
                  -Inherited disease


                    PROBIOTICS                                                  COSMETICS

                   Keeping probiotic                                           Enabling the use of probiotics
                   bacteria intact                                             and stem cell in cosmetics
                   -Probiotics for humans                                      -Soap with
                   -Animal feed                                                encapsulated .probiotic bacteria.


                            AGRICULTURAL                       ENVIRONMENTAL

                           New ideas for more efficient        Innovative solution to
                           farming and -seed improvement       environmental Problem
                            -Encapsulation of seeds             -Clean up of oil spills

          Cell in a box訂購資訊

           品 號           品 名                                  說 明                                         包 裝

                                                              一個kit可做5次實驗;產生120各膠囊; 每個膠
           SI-CIB001     Cell-in-a-Box Cell Encapsulation Kit                                             1 kit
                                                              囊約有4000~40000顆細胞

          參考文獻

          1.Löhr M, Hoffmeyer A, Kröger J, Freund M, Hain J, Holle A, Karle P, Knöfel WT, Liebe S, Müller P, Nizze H, Renner M, Saller RM,
           Wagner T, Hauenstein K, Günzburg WH, Salmons B. Lancet. Microencapsulated cell-mediated treatment of inoperable pancreatic
           carcinoma. (2001) May 19;357(9268):1591-2.
          2.Stadlbauer, V., Stiegler, P.B., Schaffellner, S., Hauser, O., Halwachs, G., Iberer, F., Tscheliessnigg, K.H. and Lackner, C. (2006)
           Morphological and functional characterization of a pancreatic beta-cell line microencapsulated in sodium cellulose
           sulfate/poly(diallyldimethylammonium chloride). Xenotransplantation 13, 337-344.
          3.Stiegler, P., Stadlbauer, V., Hackl, F., Iberer F., Lackner, C., Hauser, O., Schaffellner, S., Strunk, D., Tscheliessnigg, K.H. (2009)
           Xenotransplantation of NaCS microencapsulated porcine islet cells in diabetic rats. Organ Biology, 16(1) : 104.
          4.Salmons, B., Brandtner, E.M., Hettrich, K. Wagenknecht, W., Volkert, B., Fischer, S., Dangerfield, J.A. and Gunzburg,W.H. (2010)
           Encapsulated cells to focus the metabolic activation of anti-cancer drugs. Current Opinion in Molecular Therapeutics 12(4):450-60.
          5.Chua, A.J.S., Brandtner, E.M., Dangerfield, J.A., Salmons, B., Gunzburg, W.H. and Ng, M.L. (2010) A novel cell encapsulation mode
           for delivery of therapeutic antibodies against West Nile Virus infections that maintains steady plasma antibody levels throughout
           therapy. International Congress on Infectious Diseases (ICID): Abstract 24.010. doi:10.1016/jijid.2010.02.
          6.Salmons, B., Dangerfield, J.A., Brandtner, E.M., Toa, P., Tan, W Jin and Gunzburg, W.H. (2010) A method for protecting therapeutic
           cells and microenvironment containment in patients for gene and cell therapies: a clinically proven enabling cell encapsulation
           technology. Human Gene Therapy 21 1476-1477.
          7.Salmons, B. and Gunzburg, W.H. (2010) Therapeutic application of cell microencapsulation in cancer. Advances in Experimental
           Medicine and biology 670, 92-103.


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