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   CRISPR 線上講座
   From Bench to Bedside: Targeted Gene Editing

    時間: Sep 28, 2022  10PM (台灣時間)

    講者: Jennifer Bennett   
                PhD, Molecular Cell Biology
 

講座內容

CRISPR/Cas gene editing technology has rapidly evolved over the last decade. Its versatility extends from creating targeted research-use disease models in cells and animals, to high-throughput screening applications, to clinical reagents for cell-based therapies. The choice of CRISPR reagents is integral to the efficiency and outcome of your gene editing experiments. The specificity and precision of CRISPR tools have evolved from generic WT variants to high-fidelity variants, single base editors, and prime editors. The formats for these tools have also evolved from plasmids to ribonucleoprotein complexes and one-part, modified synthetic guides. In this webinar, we’ll discuss how next generation tools, such as PURedit™ CRISPR reagents, can take your research from discovery to the clinic. We’ll provide an overview of the important characteristics of a gene editing experiment to consider when choosing CRISPR reagents for your translational experiments, such as off-target effects and quality grades.
 
講座主題
  • Current and novel approaches to targeted gene editing
  • CRISPR tools required for targeted gene editing workflows
  • Use of PURedit™ CRISPR reagents in a variety of applications to provide enhanced specificity without sacrificing cutting activity
您將學到
  • Explore the key requirements of CRISPR reagents for preclinical and translational research
  • Understand performance and quality characteristics of gene editing reagents that make them ideal for preclinical research
  • Choosing the right CRISPR reagents for your workflow and application

PURedit sgRNA & Cas9 Protein

PURedit sgRNA 和 Cas9  Protein 提供了兩全其美的優勢。經心設計,滿足卓越的製造標準,每次都能實現一致的高質量性能。

 

活性與專一性為業界領先的高保真度 Cas 9。
業界領先 HPLC 純化 sgRNA 有效降低毒性。
最困難標的基因觀察到更高的編輯效果。
專為轉研究而設計,具最高性能、純度和質量的標準。

Guaranteed CRISPR Editing

PURedit™ gRNA  具品質和表現保證,包含客製化序列。若 gRNA 在預期目標位點沒有產生可檢測的的切割,將會提供免費的一次性換貨。
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PURedit™ CRISPR RNPs 在不同的細胞模式,展現高度 on-target 基因編輯效率與低脫靶效應的切割

Combine PURedit™ Guide RNAs with PURedit™ Cas9 for Ribonucleoprotein (RNP) Delivery