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CRISPR
線上講座
From Bench to
Bedside: Targeted Gene
Editing
時間: Sep 28, 2022
10PM (台灣時間)
講者: Jennifer
Bennett
PhD, Molecular Cell
Biology
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講座內容 CRISPR/Cas
gene editing technology has rapidly evolved over
the last decade. Its versatility extends from
creating targeted research-use disease models in
cells and animals, to high-throughput screening
applications, to clinical reagents for
cell-based therapies. The choice of CRISPR
reagents is integral to the efficiency and
outcome of your gene editing experiments. The
specificity and precision of CRISPR tools have
evolved from generic WT variants to
high-fidelity variants, single base editors, and
prime editors. The formats for these tools have
also evolved from plasmids to ribonucleoprotein
complexes and one-part, modified synthetic
guides. In this webinar, we’ll discuss how next
generation tools, such as PURedit™ CRISPR
reagents, can take your research from discovery
to the clinic. We’ll provide an overview of the
important characteristics of a gene editing
experiment to consider when choosing CRISPR
reagents for your translational experiments,
such as off-target effects and quality grades.
講座主題
- Current and novel approaches to targeted
gene editing
- CRISPR tools required for targeted gene
editing workflows
- Use of PURedit™ CRISPR reagents in a variety
of applications to provide enhanced specificity
without sacrificing cutting activity
您將學到
- Explore the key requirements of CRISPR
reagents for preclinical and translational
research
- Understand performance and quality
characteristics of gene editing reagents that
make them ideal for preclinical research
- Choosing the right CRISPR reagents for your
workflow and application
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PURedit
sgRNA & Cas9
Protein | | | |
PURedit
sgRNA 和 Cas9 Protein
提供了兩全其美的優勢。經心設計,滿足卓越的製造標準,每次都能實現一致的高質量性能。
√ 活性與專一性為業界領先的高保真度
Cas 9。
√ 業界領先
HPLC 純化 sgRNA 有效降低毒性。
√ 最困難標的基因觀察到更高的編輯效果。
√ 專為轉研究而設計,具最高性能、純度和質量的標準。
Guaranteed CRISPR
Editing
PURedit™
gRNA 具品質和表現保證,包含客製化序列。若 gRNA
在預期目標位點沒有產生可檢測的的切割,將會提供免費的一次性換貨。 | | |
PURedit™
CRISPR RNPs
在不同的細胞模式,展現高度
on-target
基因編輯效率與低脫靶效應的切割。 | | | |
Combine
PURedit™ Guide RNAs with PURedit™ Cas9 for
Ribonucleoprotein (RNP)
Delivery | | | |
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